Introduction. Multiple sclerosis is a disease that contributes to the emergence and deepening of disability. Problems in patients diagnosed with MS relate not only to the physical sphere in which the dysfunction of motor function and functional organs is observed, but also complex psychological problems in the process of coping with progressive and debilitating disease. Aim. The aim of the study was to assess the quality of life of patients with multiple sclerosis and to determine the impact of disease and other factors on the patients’ life satisfaction. Material and method. The study was conducted in a group of 100 patients with diagnosed multiple sclerosis (MS). A standardized MSIS questionnaire was used to assess the quality of life MSIS – 29. The results were analyzed statistically using the STATISTICA package. Results. The average value of points obtained in the analysis of the psychological sphere was X = 40.33. This sphere was rated a bit worse compared to the physical sphere, where the average was X = 40.61. The age (p = 0.000) and the duration of the disease (p = 0.000) significantly influenced the assessment of the two spheres of life in patients. The relapsing-chronic and secondary-chronic forms significantly reduce the quality of life in patients. Conclusions. The quality of life in the group of patients with diagnosed SM is unsatisfactory. Women more often indicate psychological problems that are a consequence of illness, while men can not come to terms with problems related to the functionality of the body. Professionally active people assess the quality of life better than unemployed persons and pensioners.

Key words: quality of life, multiple sclerosis, MSIS – 29.